1566 Thomas Hall
Assistant Professor of Entomology
My lab is interested in understanding how Medea, a unique class of maternal-effect selfish genes found in flour beetles, gains an advantage over its wild-type counterpart. Each Medea allele is bifunctional, encoding both a maternally loaded “poison” and a zygoticly expressed “antidote”. These properties favor the transmission of the M allele to subsequent generations at the expense of the non-M allele, and account for their “selfish” behavior. Elucidating the molecular mechanism responsible for this selfish behavior may facilitate the development of new gene-drive systems for pushing desirable traits into arthropod populations. My lab is also developing non-traditional transgenic technologies that are expected to make germline transformation feasible in a wider-range of pest species.